Central nesfatin-1 reduces the nocturnal food intake in mice by reducing meal size and increasing inter-meal intervals
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چکیده
منابع مشابه
Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats.
The mechanisms by which OB protein controls food intake and energy balance are unknown. Therefore, we investigated the effects of a novel modified human recombinant OB protein (Mod-OB) on spontaneous feeding patterns, body weight, running wheel activity, and ovarian cycling in female rats. Mod-OB or vehicle was injected (4 mg ⋅ kg-1 ⋅ day-1sc) for 2 ovarian cycles (8 days) using a within-subjec...
متن کاملChronic administration of OB protein decreases food intake by selectively reducing meal size in male rats.
The potent hypophagic effect of OB protein (OB) is well established, but the mechanism of this effect is largely unknown. We investigated the effects of chronic administration of a novel modified recombinant human OB (Mod-OB) with a prolonged half-life (>48 h) on ad libitum food intake, spontaneous meal patterns, and body weight in 24 adult, male Sprague-Dawley rats (body weight at study onset:...
متن کاملThe GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size.
Exendin-4 (Ex4), a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, has been shown to reduce food intake and suppress gastric emptying in rodents and humans. In this study we investigated the effects of peripheral administration of Ex4 on food intake and meal patterns in adult male rhesus macaques. Rhesus macaques (n = 4) that had been trained to lever press for food pellets were i...
متن کاملSlimming starters. Intake of a diet-congruent food reduces meal intake in active dieters
Dietary restraint is known to break down in the face of tempting foods. Previous research suggests exposure to cues associated with slimming such as images or odours act as prompts to restrict intake of a tempting snack in dieters. The effects of consuming diet-congruent foods on subsequent intake of a meal have not yet been investigated. Thus, using a repeated measures design 26 female partici...
متن کاملPre-meal anxiety and food intake in anorexia nervosa.
Anorexia nervosa (AN) is a serious mental illness characterized by reduced caloric intake that often persists after acute weight restoration. This preliminary study assesses the relationship between pre-meal anxiety and food intake in recently weight-restored individuals with AN. We hypothesized that pre-meal anxiety is inversely related to caloric intake in AN. Caloric intake and pre-meal anxi...
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ژورنال
عنوان ژورنال: Peptides
سال: 2011
ISSN: 0196-9781
DOI: 10.1016/j.peptides.2010.09.027